Article Text
Letter
Regarding minimal clinically relevant differences for superiority margins
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Being familiar with the relevant previous work of authors Shafiq and Malhotra, I read with interest their recent letter with Gamad concerning reporting of the Canakinumab Anti-Inflammatory Thrombosis Outcome Study (CANTOS).1 That trials such as CANTOS continue to be reported with claims of superiority without consideration of asymmetry in error margins …
Footnotes
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.
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