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Contributors JT and SEP contributed to the content and writing of this article.
Funding The Evidence Synthesis Working Group is funded by the National Institute for Health Research School for Primary Care Research (NIHR SPCR) (Project Number 390).
Disclaimer The views expressed are those of the author(s) and not necessarily those of the NIHR, the NHS or the Department of Health.
Competing interests SEP is currently working with the NIHR funded Evidence Synthesis Working Group. JT directs development of EPPI-Reviewer software.
Provenance and peer review Commissioned; internally peer reviewed.