Table of contents

Commentaries

• General medicine: Tiotropium could provide benefits in the early stage of COPD, but further studies are needed (27 June, 2018)

  Mario Cazzola, Paola Rogliani
• General medicine: Calcium and vitamin D do not prevent fractures in community-dwelling adults (21 June, 2018)

  Ian R Reid
• Primary care: Walking lowers mortality risk in older US adults (5 May, 2018)

  Klaus Gebel, Ding Ding
• Primary care: Blood pressure-lowering treatment lowers mortality and cardiovascular disease risk, but whether effects differ at an arbitrary threshold of 140 mm Hg systolic blood pressure requires further research (24 May, 2018)

  Dexter Canoy, Kazem Rahimi
• Primary care: Rivaroxaban plus aspirin, compared with aspirin alone, reduced cardiovascular events in patients with stable peripheral or carotid artery disease, but increased the risk of major bleeding (12 April, 2018)

  Jonathan Mant
• Maternal and child health: There is a linear association between decreasing Apgar scores at 5 and 10 min and adverse neurodevelopmental outcomes (29 June, 2018)

  Torstein Vik, Ragnhild Støen, Stian Lydersen
• Maternal and child health: Antenatal magnesium sulfate treatment for women at risk of preterm birth is safe and might decrease the risk of cerebral palsy (19 June, 2018)

  Lene Drasbek Huusom, Hanne Trap Wolf
• Emergency care: Combination of ibuprofen and acetaminophen is no different than low-dose opioid analgesic preparations in relieving short-term acute extremity pain (26 April, 2018)

  Francesca L Beaudoin