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Commentary on: Raskob GE, van Es N, Verhamme P, et al. Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med. 2018 Feb 15;378:615–624.
Low-molecular-weight heparin (LMWH) is the standard of care for treatment of cancer-associated venous thromboembolism (VTE).1 2 This recommendation is supported largely by a landmark randomised controlled trial (RCT) that showed that patients with cancer who received 6 months of dalteparin instead of warfarin (after an initial 5–7 days of dalteparin) had a 52% risk reduction for recurrent VTE.3 However, LMWH injections can be painful as well as anxiety provoking. A pill would be a welcome alternative for most patients, but only if it is as …
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