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27 Increasing prescription of opioid analgesics and neuropathic pain medicines for spinal pain in australia
  1. Stephanie Mathieson1,
  2. Lisa Valenti2,
  3. Christopher Maher3,
  4. Helena Britt2,
  5. Qiang Li4,
  6. Andrew McLachlan5,
  7. Christine Lin3
  1. 1Musculoskeletal Health Sydney, University of Sydney, Sydney, Australia
  2. 2Family Medicine Research Centre, University of Sydney, Parramatta, Australia
  3. 3Musculoskeletal Health Sydney, Sydney, Australia
  4. 4The George Institute for Global Health, Newtown, Australia
  5. 5Faculty of Pharmacy and Centre for Education and Research on Ageing, The University of Sydney, Concord, Australia


Objectives Limited evidence exists on secular trends of analgesic medicines for spinal pain. We investigated general practitioner’s (GP) recommendations of analgesic medicines for spinal pain and investigated characteristics associated with their recommendation.

Method We accessed data on spinal pain consultations from the Bettering the Evaluation and Care of Health (BEACH) database, a nationally representative database on GP activity in Australia. Data extracted included consultation details and management provided. Medicines recommended were grouped as simple analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), opioid analgesics or neuropathic pain medicines. Multivariate logistic regression determined if patient characteristics and GP characteristics were associated with medication recommendations.

Results We analysed BEACH data for 9100 GPs who managed 39 303 patients with spinal pain between 2004 and 2014. Over the decade, analgesic recommendations increased. After accounting for patient and GP characteristics, there was a significant increase in the rate single-ingredient opioid analgesics (e.g. oxycodone) [annual relative increase of 6% (Rate Ratio (RR) 1.06 (95% CI 1.05 to 1.07)] and neuropathic pain medicines (e.g. pregabalin) [annual relative increase of 19% (RR 1.19 (95% CI 1.16 to 1.22)] were recommended; and a significant decrease in the rate NSAIDs were recommended [annual relative decrease of 4% (RR 0.96 (95% CI 0.95 to 0.97)]. Logistic regression identified several patient and GP characteristics associated with medicine recommendations, e.g. stronger opioids were less likely recommended for Indigenous patients [Odds Ratio 0.15 (95% CI 0.04 to 0.56)].

Conclusions GP’s analgesic recommendations for spinal pain have become increasingly divergent from guideline recommendations over time.

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