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EBM verdict
Primary care
Should blood pressure medications be taken at bedtime?
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  • Published on: 7 February 2020
    UK TIME study will also provide further evidence
    • Amy Rogers, Clinical Research Fellow University of Dundee

    Thank you for this measured summary of the recently published HYGIA trial. I am pleased to see you mention the BedMed study ongoing. Readers may be interested to know that there is another study, already in follow-up, which will provide further evidence on whether night-time dosing of blood pressure medications really is better in the prevention of cardiovascular events and mortality.

    The University of Dundee's Treatment in Morning vs Evening (TIME, www.timestudy.co.uk) study, funded by the British Heart Foundation, aims to answer the same research question. TIME has recruited 21,104 participants across the UK and should finish in the first half of 2020.

    Conflict of Interest:
    The author works as a clinical research fellow in the TIME study.