Association of study design features and treatment effects in trials of chronic medical conditions: a meta-epidemiological study

Zhen Wang; Fares Alahdab; Magdoleen Farah; Mohamed Seisa; Mohammed Firwana; Rami Rajjoub; Samer Saadi; Tabinda Jawaid; Tarek Nayfeh; Mohammad Hassan Murad

doi:10.1136/bmjebm-2021-111667

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Original research

General medicine

Association of study design features and treatment effects in trials of chronic medical conditions: a meta-epidemiological study

Authors

Zhen Wang The Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Fares Alahdab Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Magdoleen Farah Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Mohamed Seisa Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Mohammed Firwana Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Rami Rajjoub Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Samer Saadi Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Tabinda Jawaid Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Tarek Nayfeh Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA PubMed articles Google scholar articles
Mohammad Hassan Murad The Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA Mayo Clinic Evidence-based Practice Center, Rochester, MN, USA Preventive Medicine, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles

Correspondence to Zhen Wang, Health Care Policy and Research, Mayo Clinic Minnesota, Rochester, MN 55905, USA; Wang.Zhen{at}mayo.edu

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Citation

Wang Z, Alahdab F, Farah M, et al

Association of study design features and treatment effects in trials of chronic medical conditions: a meta-epidemiological study

BMJ Evidence-Based Medicine 2022;27:104-108.

Publication history

Accepted May 29, 2021
First published July 1, 2021.

Online issue publication

March 23, 2022

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