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When we move cancer drugs from the second or third to the first line of treatment: what lessons can we learn from KEYNOTE-177 and JAVELIN-100

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  • Contributors VP developed the concept of the paper and provided critical revision. MSK drafted the paper. Both authors approved the final paper and are accountable for all aspects of the work.

  • Funding VP was funded by Arnold Ventures.

  • Competing interests VP discloses: Research funding from Arnold Ventures, royalties from Johns Hopkins Press, Medscape and MedPage, consulting fees from UnitedHealthcare, speaking fees from eviCore and New Century Health and other (Plenary Session podcast has Patreon backers).

  • Provenance and peer review Not commissioned; externally peer reviewed.