Footnotes

• Twitter @dnunan79, @gabrielgcnut, @yluo06, @InsideTrials

• Contributors DN conceived the idea for the manuscript and led the development and write up. DN, KBashir, KBilimoria, JB, FC, RD, MBD, GGC, MMG, AH, MSH, SK, KKK, AL-J, YL, NM, RTDM, RLM, CS, VS, JS and UNY contributed to the selection of included papers, manuscript write up and agreed upon the final submitted version of the manuscript. DN acts as guarantor.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Disclaimer The views expressed in this article represent the views of the authors and not necessarily those of their host institutions or any organisations they may be affiliated with or have received funding from.

• Competing interests DN has received expenses and fees for his media work. He holds grant funding from the NIHR School of Primary Care Research and the Royal College of General Practitioners. On occasion, he receives expenses for teaching EBM. He is an associate editor at the BMJ Evidence Based Medicine journal. None to declare: KBashir, FC, MBD, KBilimoria, JB, GGC, RD, MMG, AH, MSH, AL-J, KKK, SK, RLM, RTDM and VS.

• Provenance and peer review Not commissioned; externally peer reviewed.