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  • Transcervical resection of the endometrium was effective and acceptable at up to 2 years for heavy menstrual bleeding

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Therapeutics
Transcervical resection of the endometrium was effective and acceptable at up to 2 years for heavy menstrual bleeding

https://doi.org/10.1136/ebm.5.1.24

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    (1999) Br J Obstet Gynaecol 106, 258. Cooper KG, Parkin DE, Garratt AM, et al.. Two-year follow up of women randomised to medical management or transcervical resection of the endometrium for heavy menstrual loss: clinical and quality of life outcomes.. Mar;. :. –65.
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 QUESTION: In women with heavy menstrual bleeding, is transcervical resection of the endometrium (TCRE) better than medical management for relieving menstrual symptoms in the long term?

    Design

    Randomised (concealed*)†, unblinded,* controlled trial with 2-year follow-up.

    Setting

    Gynaecology department of a large hospital in Scotland.

    Patients

    187 women who consulted a gynaecologist for the first time for heavy menstrual bleeding, were not going to have more children, had a clinical diagnosis of dysfunctional uterine bleeding, had not been referred for surgery, and did not have a treatment preference. Follow-up was 93% (mean age 42 y).

    Intervention

    Women were allocated to TCRE (n=93) or medical management (n=94). Medical management consisted of progestogens, combined oral contraceptive pill, tranexamic acid, danazol, or hormone replacement therapy and non-steroidal anti-inflammatory …

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    Footnotes

    • Source of funding: Scottish Office Department of Health.

    • For correspondence: Dr K G Cooper, Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZB, UK.

    • ↵* See glossary.

    • ↵† Cooper KG, Parkin DE, Garratt AM, et al. Br J Obstet Gynaecol 1997;104:1360–6.

    • ↵‡ p value calculated from data in article.