Therapeutics
Controlled- and extended-release metoprolol reduced mortality in congestive heart failure
MERIT-HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet1999 Jun 12;353:2001–7.
Abciximab and stenting reduced death, myocardial infarction, and repeated revascularization in coronary revascularization
Lincoff AM, Califf RM, Moliterno DJ, et al, for the Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators. Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. N Engl J Med1999 Jul 29;341:319–27.
Cognitive behavioral therapy reduced noncardiac chest pain and use of psychological services
van Peski-Oosterbaan AS, Spinhoven P, van Rood Y,et al. Cognitive-behavioral therapy for noncardiac chest pain: a randomized trial. Am J Med1999Apr;106:424–9.
Low-dose aspirin reduced combined 3-month risk for stroke, MI, and death after cartoid endarterectomy
Taylor DW, Barnett HJ, Haynes RB, et al, for the ASA and Carotid Endarterectomy (ACE) Trial Collaborators. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. Lancet1999Jun 26;353:2179–84.
Tissue plasminogen activator improved function at 6 and 12 months after ischemic stroke
Kwiatkowski TG, Libman RB, Frankel M, et al., for the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study Group. Effects of tissue plasminogen activator for acute ischemic stroke at one year. N Engl J Med1999Jun 10;340:1781–7.
Review: treatment of gastroesophageal reflux does not improve asthma outcomes
Gibson PG, Henry RL, Coughlan JL. The effect of treatment for gastro-oesophageal reflux on asthma in adults and children. Cochrane Review, latest version 10 Feb 1999. In: Cochrane Library. Oxford: Update Software.
Review: the effectiveness of acupuncture for nonspecific low-back pain is unclear
van Tulder MW, Cherkin DC, Berman B,et al. The effectiveness of acupuncture in the management of acute and chronic low back pain: a systematic review within the framework of the Cochrane Collaboration Back Review Group. Spine1999Jun 1;24:1113–23.
Therapeutic NCPAP was more effective than subtherapeutic NCPAP in obstructive sleep apnea
Jenkinson C, Davies RJ, Mullins R,et al. Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial. Lancet1999Jun 19;353:2100–5.
Neostigmine improved acute colonic pseudo-obstruction quickly and effectively
Ponec RJ, Saunders MD, Kimmey MB. Neostigmine for the treatment of acute colonic pseudo-obstruction. N Engl J Med1999Jul 15;341:137–41.
Plasma volume expansion with albumin reduced renal impairment and death in cirrhosis and spontaneous bacterial peritonitis
Sort P, Navasa M, Arroyo V,et al. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med1999Aug 5;341:403–9.
Endoscopic ligation was better than propranolol for prevention of bleeding from esophageal varices
Sarin SK, Lamba GS, Kumar M,et al. Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. N Engl J Med1999Apr 1;340:988–93.
Ramipril reduced the rate of progression to end stage renal disease and overt proteinuria in non-diabetic nephropathy
Ruggenenti P, Perna A, Gherardi G,et al. Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria. Lancet1999Jul 31;354:359–64.
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