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Therapeutics
Review: antibiotics have a slight beneficial effect on acute bronchitis

https://doi.org/10.1136/ebm.5.2.42

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    (1999) Am J Med 107, 62. Bent S, Saint S, Vittinghoff E, et al.. Antibiotics in acute bronchitis: a meta-analysis.. Jul;. :. –7.
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 QUESTION: In patients with acute bronchitis, do antibiotics reduce sputum production, cough, or days off work?

    Data sources

    English language studies were identified in Medline (1966 to April 1998) by using the terms drug therapy, bronchitis, and acute disease; the reference lists of relevant articles were reviewed, and experts in the field were contacted.

    Study selection

    Studies were selected if they were randomised controlled trials that compared antibiotics with placebo in patients who had acute bronchitis but no history of chronic lung disease or pneumonia, therapy was given for ≥5 days, and effect sizes could …

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    Footnotes

    • Source of funding: no external funding.

    • For correspondence: Dr S Bent, General Internal Medicine Section, San Francisco Veterans Affairs Medical Center 111A1, 4150 Clement Street, San Francisco, CA 94121, USA.Fax +1 415 386 4044.