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  • Review: multiple interventions modestly reduce cardiovascular risk factors in primary prevention, but effects on mortality are uncertain

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Therapeutics
Review: multiple interventions modestly reduce cardiovascular risk factors in primary prevention, but effects on mortality are uncertain

https://doi.org/10.1136/ebm.5.2.48

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    . Ebrahim S, Davey Smith G. Multiple risk factor interventions for primary prevention of coronary heart disease. Cochrane Review, latest version 24 Feb 1999. In: the Cochrane Library. Oxford: Update Software..

    
 
 QUESTION: In people who show no evidence of established cardiovascular disease, how effective is counselling or educational interventions aimed at controlling risk factors in reducing all cause and coronary artery disease (CAD) mortality?

    Data sources

    Studies were identified by using Medline (1966 to April 1995) and bibliographies of relevant studies and by contacting experts.

    Study selection

    Studies were selected if they were randomised controlled trials with ≥6 months of follow up of counselling or educational interventions with or without medications aimed at controlling ≥1 cardiovascular risk factor (blood pressure, smoking, total blood cholesterol level, physical activity, and diet) in people ≥40 years of age who show …

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    Footnotes

    • Sources of funding: NHS Centre for Reviews and Dissemination and Health Education Authority.

    • For correspondence: Professor S Ebrahim, Epidemiology of Ageing, Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK. Fax +44 117 928 7325.

    • A modified version of the abstract also appears in Evidence- Based Nursing.