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QUESTION: In children with acute asthma, are homemade spacers as effective as conventional ones for improving response to a β2 agonist given by metered dose inhaler?
Design
Randomised {allocation concealed*}†, blinded (outcome assessors),* controlled trial with 15 to 30 minute follow up.
Setting
A children's hospital in South Africa.
Patients
88 children, 5 to 13 years of age (mean age 10 y, 60% boys, 50% moderate to severe airway obstruction [peak expiratory flow rate {PEFR} 20% to 59% of predicted normal value]), with a history of asthma, and presented with an acute asthma attack. Exclusion criteria were inability to use a metered dose inhaler (MDI) and spacer or to have pulmonary function tests with PEFR <20% of the predicted …
Footnotes
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Source of funding: Medical Research Council of South Africa.
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For correspondence: Dr H Zar, Child Health Unit, 46 Sawkins Road, Rondebosch, South Africa 7700. Fax +27 27 21 689 5403.
↵† Information supplied by author.