You are here

Article Text

Article menu
Download PDFPDF
Therapeutics
Antidepressants plus cognitive therapy reduced relapse in residual depression

https://doi.org/10.1136/ebm.5.3.87

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    (1999) Arch Gen Psychiatry 56, 829. Paykel ES, Scott J, Teasdale JD, et al.. Prevention of relapse in residual depression by cognitive therapy. A controlled trial.. Sep;. :. –35.
    OpenUrlCrossRefPubMedWeb of Science

    
 
 QUESTION: In patients with residual depressive symptoms who continue to receive maintenance antidepressant treatment, does cognitive therapy (CT) reduce relapse rates?

    Design

    Randomised {allocation concealed*}†, blinded (outcome assessors),*r; controlled trial with 1 year follow up.

    Setting

    2 psychiatric outpatient clinics, Cambridge and Newcastle, UK.

    Patients

    158 patients between 21 and 65 years of age (mean age 43 y, 51% men) with unipolar depression, satisfying the Diagnostic and Statistical Manual of Mental Disorders, 3d edition, Revised (DSM-III-R) criteria for major depression within the previous 18 months but not in the previous 2 months, and who had residual symptoms (lasting 2 to 18 mo) reaching at least 8 on the 17 item Hamilton Depression Rating Scale and 9 on the Beck Depression Inventory. Exclusion criteria were history of bipolar disorders, cyclothymia, schizoaffective disorder, drug or alcohol dependence, …

    View Full Text

    Footnotes

    • Source of funding: Medical Research Council, London, and Oxford and Anglia Region.

    • For correspondence: Dr ES Paykel, Department of Psychiatry, University of Cambridge, Box 189, Addenbrook's Hospital, Cambridge CB2 2QQ, England. FAX +44 (0)1223 336968.

    • ↵* See glossary.

    • ↵† Information provided by author.