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Therapeutics
Review: β sitosterols improve urinary symptoms in the short term in men with benign prostatic hyperplasia

https://doi.org/10.1136/ebm.5.3.90

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    . Wilt T, Ishani A, Mac Donald R, et al. Beta-sitosterols for benign prostatic hyperplasia. Cochrane Review, latest version 19 July 1999. In: the Cochrane Library. Oxford: Update Software..

    
 
 QUESTION: In men with benign prostatic hyperplasia (BPH), are β sitosterols effective for improving urinary symptoms?

    Data sources

    Studies were identified by searching Medline (1966 to July 1998), EMBASE/Excerpta Medica (1974 to July 1998), Phytodok, the Cochrane Library, and bibliographies of relevant studies and by contacting authors.

    Study selection

    Studies were selected if they were randomised controlled trials (RCTs) of β sitosterol treatment for ≥30 days in men with symptomatic BPH.

    Data extraction

    2 reviewers independently assessed the quality of study methods and extracted data on patients, intervention, and outcomes (urological symptom scores, urodynamic measures, mean urine flow, residual urine volume, nocturia, and …

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    Footnotes

    • Source of funding: no external funding.

    • For correspondence: Mr R Mac Donald, General Internal Medicine (111-0), Minneapolis VA/VISN 13 Center for Chronic Diseases Outcomes Research, 1 Veterans Drive, Minneapolis, MN 55417, USA. Fax +1 612 725 1964.