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Therapeutics
Pacifiers have greater analgesic effect than sweet solutions during venipuncture in full term newborns

https://doi.org/10.1136/ebm.5.4.122

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    (1999) BMJ 319, 1393. Carbajal R, Chauvet X, Couderc S, et al. . Randomised trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates.. Nov 27;. :. –7..
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 QUESTION: In full term newborns having venipuncture, what are the analgesic effects of glucose, sucrose, and pacifiers?

    Design

    Randomised (allocation concealed*), blinded (outcome assessor was blinded to type of solution but not to the pacifier),* placebo controlled trial.

    Setting

    Maternity ward of a hospital in Poissy, France.

    Patients

    150 eligible newborns (59% boys) who had a 5 minute Apgar score ≥7, were medically stable, had not received naloxone during the previous 24 hours, and were not fed in the previous 30 minutes. 50 eligible newborns were not randomised because of non-availability of the observer …

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    Footnotes

    • Source of funding: no external funding.

    • For correspondence: Dr R Carbajal, Department of Paediatrics, Poissy Hospital, 78300 Poissy, France. Fax +33 1 39 27 44 33.

    • ↵* See glossary.