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QUESTION: In adults who have symptoms of dyspepsia and consult a general practitioner, is a near patient test (FlexSure) accurate for detecting Helicobacter pylori infection?
Blinded comparison of a near patient test with an enzyme linked immunosorbent assay (ELISA) within a randomised controlled trial of 4 management strategies for dyspepsia.
43 general practices in Nottinghamshire, England.
762 adults who were 18–73 years of age (mean age 42 y) and had symptoms of dyspepsia of sufficient severity to justify empiric treatment with H2-antagonists or proton pump inhibitors. Exclusion criteria were symptoms consistent with malignant tumors, a history of peptic ulcer or reflux esophagitis, investigation for dyspepsia in the previous 5 years, treatment in the previous 6 months with non-steroidal anti-inflammatory drugs or H pylori eradication treatment, or ≥3 prescriptions in the previous 6 months for acid …
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