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Therapeutics
Weight loss in obese patients with asthma improved lung function and health status

https://doi.org/10.1136/ebm.5.6.170

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    (2000) BMJ 320, 827. Stenius-Aarniala B, Poussa T, Kvarnström J. , et al. . Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study.. Mar 25;. :. –32..
    OpenUrlAbstract/FREE Full Text

    
 
 QUESTION: In obese patients with asthma, does weight loss improve lung function and health status and alleviate symptoms?

    Design

    Randomised (allocation concealed*), unblinded,* controlled trial with 1 year follow up.

    Setting

    Outpatient clinic in Helsinki, Finland.

    Patients

    38 patients who were 18–60 years of age (mean age 49 y, 76% women), had a body mass index of 30 to 42, had asthma with a spontaneous diurnal variation or a bronchodilator response of ≥15%, and were non-smokers. Exclusion criteria were pregnancy; history of bulimia or anorexia; other severe disease, including heart, thyroid, liver, or gallbladder disorders; insulin or systemic steroid treatment; or history of food allergy or intolerance to any element of the intervention diet. Follow up was complete.

    Intervention

    Patients were allocated to a weight loss group (n=19) or …

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    Footnotes

    • Sources of funding: Finnish Culture Foundation; Association of the Pulmonary Disabled; Wilhelm and Else Stockmann Foundation.

    • For correspondence: Dr B Stenius-Aarniala, Department of Medicine, University Central Hospital, PL 340 Helsinki, FIN-00029 HYKS, Finland.

    • ↵* See glossary.