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Angioplasty was no better than medication for reducing blood pressure or slowing disease progression in renal artery stenosis
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 QUESTION: In patients with atherosclerotic renal artery stenosis who have normal or mildly impaired renal function, is balloon angioplasty as effective as antihypertensive drug treatment for reducing blood pressure?

Design

Randomised (allocation concealed*), blinded {outcome assessors},* controlled trial with 12 months follow up.

Setting

26 clinical centres in the Netherlands.

Patients

106 patients (mean age 60 y, 62% men) with renal artery stenosis measured by renal arteriography (reduction in luminal diameter ≥50%) and normal to mildly impaired renal function (serum creatinine level ≤2.3 mg/dl [200 μmol/l]). Exclusion criteria were cancer, hypertension caused by a condition other than renovascular disease, unstable coronary artery disease, heart failure, or pregnancy. Follow up was 98%.

Intervention

56 patients were allocated to …

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