Article Text

Download PDFPDF

Risk for mother to child HIV-1 infection was increased by breast feeding
Free

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


 
 QUESTION: In the infants of HIV-1 infected women, does formula feeding instead of breast feeding reduce the rate of HIV-1 transmission and mortality?

Design

Randomised (allocation concealed*), blinded (investigators to interim results),* controlled trial with 2 year follow up.

Setting

4 antenatal clinics in Nairobi.

Patients

425 HIV-1 infected pregnant women (mean age 23 y) who resided in Nairobi and had access to municipally treated water. 401 mother-infant pairs (94%) were included in the analysis.

Intervention

Women were allocated to breast feed (n=212) or formula feed (n=213) their infants. Women in the formula feed group were told to feed their infant with a cup and had to demonstrate proper formula preparation and cup feeding to a visiting nurse.

Main outcome measures

Infant HIV-1 infection and mortality …

View Full Text