You are here

  • Home
  • Archive
  • Volume 5, Issue 6
  • Methadone maintenance was more effective for treatment retention for opioid dependence than psychosocially enriched detoxification

Article Text

Article menu
Download PDFPDF
Therapeutics
Methadone maintenance was more effective for treatment retention for opioid dependence than psychosocially enriched detoxification

https://doi.org/10.1136/ebm.5.6.180

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    (2000) JAMA 283:1303. Sees KL, Delucchi KL, Masson C. , et al.. Methadone maintenance vs 180-day psychosocially enriched detoxification for treatment of opioid dependence. A randomized controlled trial.. Mar 8;. :. –10.
    OpenUrlCrossRefPubMedWeb of Science

    
 
 QUESTION: In adults with opioid dependence, do standard methadone maintenance (MM) and methadone assisted detoxification plus intensive psychosocial services lead to similar outcomes?

    Design

    Randomised {allocation concealed*}†, unblinded,* controlled trial with 12 month follow up.

    Setting

    A Veterans Affairs medical centre in San Francisco, California, United States.

    Patients

    179 non-veteran adults who were ≥18 years of age (mean age 39 y, 59% men); had a diagnosis of opioid dependence according to the Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition; and tested positive for opioid use and negative for methadone use. Exclusion criteria were contraindications to methadone treatment, psychiatric medical conditions that interfered with treatment, pregnancy, lactation, concurrent substance abuse treatment, no signs of opioid withdrawal on 3 occasions, methadone treatment in the previous week, participation in a follow up phase of a previous methadone detoxification research protocol, or inability to participate for …

    View Full Text

    Footnotes

    • Source of funding: National Institute on Drug Abuse.

    • For correspondence: Dr S M Hall, Department of Psychiatry, University of California, San Francisco, 401 Parnassus Avenue, Box 0984-TRC, San Francisco, CA 94143-0984, USA. Fax +1 415 476 7677.

    • ↵* See glossary.

    • ↵† Information provided by author.