Table of contents

Therapeutics

• A computer based decision support system and risk chart did not reduce cardiovascular risk or blood pressure in hypertension (1 January, 2001)
• Long acting nifedipine was as effective as hydrochlorothiazide plus amiloride for reducing mortality and morbidity in hypertension (1 January, 2001)
• Diltiazem was as effective as diuretics or β blockers, or both, at preventing cardiovascular mortality and morbidity (1 January, 2001)
• Review: prehospital thrombolysis for acute myocardial infarction decreases short term hospital mortality (1 January, 2001)
• Review: percutaneous coronary angioplasty is associated with less angina but more coronary artery bypass grafting in patients with non-acute coronary artery disease than is medical treatment (1 January, 2001)
• Review: donepezil, metrifonate, rivastigmine, and Ginkgo biloba are more effective than placebo in Alzheimer's disease

  (1 January, 2001)
• On demand use of β₂ agonists led to better asthma control than regular use in moderate to severe asthma

  (1 January, 2001)
• Voluntary counselling and testing reduced unprotected intercourse among adults in 3 developing countries (1 January, 2001)
• Review: maximum androgen blockade does not confer additional survival benefit to androgen suppression in prostate cancer (1 January, 2001)
• Clonidine was effective for reducing tamoxifen associated hot flashes in postmenopausal women with breast cancer (1 January, 2001)
• Review: palliative chemotherapy reduces death and progression at 12 months in advanced or metastatic colorectal cancer (1 January, 2001)
• Review: smooth muscle relaxants treat abdominal pain and loperamide reduces diarrhoea in irritable bowel syndrome (1 January, 2001)
• Alosetron was effective and safe for relieving abdominal symptoms in women with irritable bowel syndrome (1 January, 2001)
• Review: 3 to 7 months of prednisone is more effective than 2 months in children with steroid responsive nephrotic syndrome (1 January, 2001)