You are here

  • Home
  • Archive
  • Volume 6, Issue 1
  • Review: palliative chemotherapy reduces death and progression at 12 months in advanced or metastatic colorectal cancer

Article Text

Article menu
Download PDFPDF
Therapeutics
Review: palliative chemotherapy reduces death and progression at 12 months in advanced or metastatic colorectal cancer

https://doi.org/10.1136/ebm.6.1.19

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    (2000) Cochrane Database Syst Rev (2). Colorectal Meta-analysis Collaboration.. Palliative chemotherapy for advanced or metastatic colo-rectal cancer.. ;. :CD001545 (latest version 16 Nov 1999). .

    
 
 QUESTION: In patients with locally advanced or meta-static colorectal cancer, what are the benefits and harms of palliative chemotherapy?

    Data sources

    Studies were identified by searching Medline, EMBASE/Excerpta Medica, CancerLit, the Cochrane Controlled Trials Register, CINAHL, HealthSTAR, Science Citation Index, Edina Biosis, NHS Economic Evaluation Database, Index to Scientific and Technical Proceedings, and PASCAL (to October 1998); handsearching conference abstracts; scanning bibliographies of relevant studies; searching sources of unpublished trials; and contacting authors.

    Study selection

    Studies in any language were selected if they were randomised controlled trials (RCTs) that compared palliative chemotherapy with supportive care alone in patients with advanced or metastatic colorectal cancer.

    Data extraction

    The quality of studies was …

    View Full Text

    Footnotes

    • Source of funding: NHS National Cancer Research & Development Programme UK.

    • For correspondence: Dr L Y Best, CRX Wessex Medical Oncology Unit, Southampton General Hospital, Level F (809), Centre Block, Southampton SO16 6YD, UK. Fax +44 (0)1703 783839.