You are here

  • Home
  • Archive
  • Volume 6, Issue 1
  • Review: 3 to 7 months of prednisone is more effective than 2 months in children with steroid responsive nephrotic syndrome

Article Text

Article menu
Download PDFPDF
Therapeutics
Review: 3 to 7 months of prednisone is more effective than 2 months in children with steroid responsive nephrotic syndrome

https://doi.org/10.1136/ebm.6.1.22

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    (2000) Arch Dis Child 83, 45. Hodson EM, Knight JF, Willis NS. , et al.. Corticosteroid therapy in nephrotic syndrome: a meta-analysis of randomised controlled trials.. Jul;. :. –51.
    OpenUrlAbstract/FREE Full Text

    
 
 QUESTION: In children with steroid responsive nephrotic syndrome (SRNS), what is the optimal corticosteroid regimen?

    Data sources

    Studies were identified by searching Medline (1966 to July 1998), EMBASE/Excerpta Medica (1988 to July 1998), and the Cochrane Controlled Trials Register (1998); scanning reference lists of relevant articles, nephrology textbooks, and proceedings of scientific meetings; and contacting investigators.

    Study selection

    2 reviewers independently selected studies if they were randomised or quasirandomised controlled trials, involved children who were 3 months to 18 years of age and had initial or subsequent episodes of SRNS, compared different regimens of prednisone or other corticosteroid agents, and reported ⩾6 months of follow up data.

    Data extraction

    2 reviewers independently extracted data on setting, publication year, number of patients in each group, dose and duration of treatments, study methods, …

    View Full Text

    Footnotes

    • Source of funding: Australian Kidney Foundation.

    • For correspondence: Dr E M Hodson, Centre for Kidney Research, Royal Alexandra Hospital for Children, PO Box 3515, Parramatta, Sydney, New South Wales 2124, Australia. Fax +61 2 9845 3432.