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  • Review: the accuracy of troponin T and I tests in acute myocardial infarction depends on timing after onset of symptoms

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Diagnosis
Review: the accuracy of troponin T and I tests in acute myocardial infarction depends on timing after onset of symptoms

https://doi.org/10.1136/ebm.6.1.25

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    (2000) J Fam Pract 49, 550. Ebell MH, Flewelling D, Flynn CA.. A systematic review of troponin T and I for diagnosing acute myocardial infarction.. Jun;. :. –6.
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 QUESTION: Are troponin T and troponin I tests accurate for detecting acute myocardial infarction (MI) at varying times from onset of symptoms or presentation to the emergency department (ED)?

    Data sources

    Studies were identified by searching Medline to December 1999 with terms and phrases related to troponin, diagnosis, and diagnostic use.

    Study selection

    English, German, French, and Spanish language studies were selected if troponin tests were used in the assessment of adults with acute chest pain, the study design included prospective data collection, assessment of acute MI was made by clinicians blinded to the results of the troponin tests, MI was diagnosed using the World Health Organisation or similar criteria, and sensitivity and specificity data were reported for ≥1 time point from the onset of pain or presentation to the ED.

    Data extraction

    Data were extracted on settings, …

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    Footnotes

    • Source of funding: Michigan Consortium for Family Practice Research.

    • For correspondence: Dr M H Ebell, Department of Family Practice, Michigan State University, B101 Clinical Center, East Lansing, MI 48824-1315, USA. Fax +1 706 549 8121.