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  • Spacers were better and less expensive than nebulisers for giving albuterol to children with moderate to severe acute asthma

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Economics
Spacers were better and less expensive than nebulisers for giving albuterol to children with moderate to severe acute asthma

https://doi.org/10.1136/ebm.6.1.31

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    (2000) J Pediatr 136, 497. Leversha AM, Campanella SG, Aickin RP. , et al. . Costs and effectiveness of spacer versus nebulizer in young children with moderate and severe acute asthma.. Apr;. :. –502.
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 QUESTION: In young children seen in the emergency department for moderate and severe acute asthma, is delivery of albuterol by metered dose inhaler (MDI) and spacer a cost effective alternative to delivery by nebuliser?

    Design

    Randomised (allocation concealed*), blinded {patients, clinicians, and outcome assessors}†,* controlled trial with 48 hour follow up.

    Setting

    A children's hospital in Auckland, New Zealand.

    Patients

    60 children who were 1 to 4 years of age (mean age 34 mo, 64% boys), had a known history of asthma, and presented to the emergency department with an acute exacerbation of asthma that was rated as moderate to severe. Exclusion criteria were inhaled bronchodilator use in the hour before presentation, immediate admission to the intensive care unit, or a co-existing medical condition, such as pneumonia. Follow up was complete.

    Intervention

    Children were allocated to albuterol, 600 μg by …

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    Footnotes

    • Sources of funding: Asthma and Respiratory Foundation of New Zealand. Boehringer Ingelheim NZ Ltd supplied the AeroChambers.

    • For correspondence: Dr A Leversha, General Paediatrics, Starship Children's Hospital, Private Bag 92-024, Auckland, New Zealand. Fax +64 9 837 8957.

    • ↵* See glossary.

    • ↵† Information provided by author.