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Clinical prediction guide
A simple clinical tool that included age, weight, and oestrogen use helped to select women for bone densitometry

https://doi.org/10.1136/ebm.6.1.32

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    (2000) CMAJ 162, 1289. Cadarette SM, Jaglal SB, Kreiger N. , et al.. Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry.. May 2;. :. –94.
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 QUESTION: Can a simple screening tool accurately identify which women are at increased risk for osteoporosis and should have bone densitometry?

    Design

    A population based cohort study, the Canadian Multicentre Osteoporosis Study (CaMos), provided data for the derivation and validation of the screening tool.

    Setting

    Hamilton, Kingston, and Toronto, Ontario, Canada.

    Patients

    1376 women ≥45 years of age (mean age 63 y, 95% white), who had had dual energy radiographic absorptiometry testing at both the femoral neck and lumbar spine (L1 to L4) and had a Mini-Mental State score >20. Exclusion criteria were previous diagnosis of osteoporosis or current use of bone active medications other than ovarian hormones. The derivation cohort comprised 926 randomly selected women, and the validation cohort comprised 450.

    Description of prediction guide

    Of 6 predictors of low bone …

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    Footnotes

    • Source of funding: University of Toronto Dean's Fund.

    • For correspondence: Dr S M Cadarette, Osteoporosis Research Program, Sunnybrook and Women's College Health Sciences Centre, 76 Grenville Street, 10th Floor East, Room 1005, Toronto, Ontario M5S 1B2, Canada. s.cadarette{at}utoronto.ca.