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A simple clinical tool that included age, weight, and oestrogen use helped to select women for bone densitometry

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 QUESTION: Can a simple screening tool accurately identify which women are at increased risk for osteoporosis and should have bone densitometry?


A population based cohort study, the Canadian Multicentre Osteoporosis Study (CaMos), provided data for the derivation and validation of the screening tool.


Hamilton, Kingston, and Toronto, Ontario, Canada.


1376 women ≥45 years of age (mean age 63 y, 95% white), who had had dual energy radiographic absorptiometry testing at both the femoral neck and lumbar spine (L1 to L4) and had a Mini-Mental State score >20. Exclusion criteria were previous diagnosis of osteoporosis or current use of bone active medications other than ovarian hormones. The derivation cohort comprised 926 randomly selected women, and the validation cohort comprised 450.

Description of prediction guide

Of 6 predictors of low bone …

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  • Source of funding: University of Toronto Dean's Fund.

  • For correspondence: Dr S M Cadarette, Osteoporosis Research Program, Sunnybrook and Women's College Health Sciences Centre, 76 Grenville Street, 10th Floor East, Room 1005, Toronto, Ontario M5S 1B2, Canada. s.cadarette{at}