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Oedema reduction by mechanical compression improved the healing of foot infection in patients with diabetes mellitus

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 QUESTION: Does aggressive oedema reduction with a foot level mechanical compression device improve healing of foot infection in patients with diabetes mellitus?


Randomised {allocation concealed*}, blinded (investigators and patients),* controlled trial with 12 weeks follow up.


University teaching hospital and related clinics in San Antonio, Texas, USA.


115 patients with diabetes who had foot infections requiring incision and debridement. Exclusion criteria were congestive heart failure, advanced renal disease, serum creatinine concentration >177 μmol/l, or planned lower extremity bypass graft surgery. 97 patients (84%) (mean age 50 y, 74% men) had complete follow up.


Patients were allocated to receive a functioning (active group, n=59) or non-functioning (placebo group, n=56) …

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  • Source of funding: Kinetic Concepts Inc, San Antonio, Texas.

  • For correspondence: Dr D G Armstrong, Department of Surgery, Southern Arizona Veterans Affairs Medical Center, 3601 South Sixth Avenue, Tucson, AZ 85723, USA. Fax +1 781 823 6628.

  • * See glossary.

  • Information provided by author.