Article Text

Download PDFPDF

Changes in diet and physical activity prevented type 2 diabetes mellitus in people with impaired glucose tolerance
Free

Statistics from Altmetric.com


 
 QUESTION: In patients with impaired glucose tolerance, is a lifestyle intervention programme effective for preventing type 2 diabetes mellitus?

Design

Randomised (allocation concealed*), unblinded,* controlled trial with mean follow up of 3.2 years (the Finnish Diabetes Prevention Study).

Setting

5 locations in Finland (Helsinki, Kuopio, Oulu, Tampere, and Turku).

Patients

522 patients between 40 and 65 years of age (mean age 55 y, 67% women) who were overweight (body mass index ≥ 25 kg/m2) and had impaired glucose tolerance (mean plasma glucose level between 7.8 and 11.0 mmol/l 2 h after receiving 75 g of oral glucose on 2 occasions, in patients with plasma glucose levels < 7.8 mmol/l after an overnight fast). Exclusion criteria included diabetes mellitus and advanced chronic disease. Follow up …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.