Statistics from Altmetric.com
QUESTION: In patients with complicated gastro-oesophageal reflux disease (GORD), how do the long term outcomes of surgical treatment compare with those of medical treatments?
Randomised (allocation concealed*), blinded (unclear),* controlled trial with a mean follow up of 10 years.
8 Veterans Affairs medical centres in the US.
247 patients (mean age 58 y) with complicated GORD. 129 of 160 surviving patients (mean age 67 y, 98% men) were included in the follow up analysis.
Patients were allocated to receive surgical treatment (n=82), continuous medical treatment (n=77), or symptomatic medical treatment (n=88). The method of surgical treatment was open Nissen fundoplication. Continuous medical treatment consisted of 2 antacid tablets, 1 and 3 hours after meals; ranitidine 150 mg twice daily; and metoclopramide 10 mg 4 times daily, and sucralfate 1 g …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.