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Clinical prediction guide
A clinical prediction model did well in diagnosing paediatric group A β-haemolytic streptococcal pharyngitis

https://doi.org/10.1136/ebm.7.1.32

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    Attia MW, Zaoutis T, Klein JD, et al. Performance of a predictive model for streptococcal pharyngitis in children.Arch Pediatr Adolesc Med2001 Jun;155:687–91.
    OpenUrlPubMedWeb of Science

    
 
 QUESTION: In children with suspected group A β-haemolytic streptococcal (GABHS) pharyngitis, how well does a prediction model predict a positive throat culture?

    Design

    1 year validation of a previously derived prediction model.

    Setting

    Paediatric emergency department and 2 paediatric outpatient clinics in Wilmington, Delaware, USA.

    Patients

    587 children (mean age 6.8 y, 51% girls) who had signs and symptoms of acute pharyngitis. Exclusion criteria were antibiotic treatment within 5 days of enrollment.

    Description of prediction guide

    During the clinical evaluation, the examining physician recorded 4 variables from the tested model: cervical lymphadenopathy, tonsillar swelling (2 category severity scale: absent or mild and moderate or severe), coryza, and scarletiniform rash (present or absent). 2 tonsillopharyngeal specimens were collected for each patient for serotyping (diagnostic standard) and a rapid streptococcal antigen detection test. Furthermore, the physician made a subjective probability estimate for …

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    Footnotes

    • Source of funding: Nemours Research Programs.

    • For correspondence: Dr M W Attia, Department of Pediatrics, Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA.mattia{at}nemours.org