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Therapeutics
Review: varicella vaccination is effective in children

https://doi.org/10.1136/ebm.7.1.9

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    (2001) Arch Dis Child 85, 83. Skull SA, Wang EE.. Varicella vaccination — a critical review of the evidence.. Aug;. :. –90.
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 QUESTION: What are the benefits and harms of varicella vaccination in children?

    Data sources

    Studies were identified by searching Medline (1966 to 2000) with the terms chickenpox, vaccination, and human, and with methodological terms to retrieve high quality controlled clinical trials and cohort studies; EMBASE/Excerpta Medica; and the Cochrane Library. The internet was searched for position papers and summaries from health organisations and vaccine product information, and reference lists of relevant articles were reviewed.

    Study selection

    Studies were selected if they were randomised controlled trials (RCTs) or cohort studies of healthy humans vaccinated with varicella zoster virus (VZV) vaccine and if they assessed the incidence of varicella, zoster, or adverse reactions to vaccination.

    Data extraction

    Data were extracted on study design, patient characteristics, length of …

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    Footnotes

    • Source of funding: not stated.

    • For correspondence: Dr S Skull, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Parkville, 3050 Victoria, Australia.