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QUESTION: What are the diagnostic accuracies of 5 non-invasive or minimally invasive tests for detecting renal artery stenosis: computed tomographic angiography (CTA), magnetic resonance angiography (MRA), ultrasonography, captopril scintigraphy, and the captopril test?
Data sources
Studies were identified by searching Medline, EMBASE/Excerpta Medica, and the Cochrane Library (to August 2000) and by scanning bibliographies of relevant studies.
Study selection
2 reviewers selected English, German, or French language studies if they used intra-arterial x ray angiography as the diagnostic standard, patients were referred for clinical suspicion of renovascular hypertension, criteria and cutoff points for positive results were explicitly defined for each test, and the number of positive and negative results were reported for both the test and the diagnostic standard. Exclusion criteria were patients with renal transplantation or possible verification bias (ie, patients with a positive result on the index …
Footnotes
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Source of funding: Dutch Health Care Insurance Board.
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For correspondence: Dr G B Vasbinder, University Hospital of Maastricht, Maastricht, The Netherlands. bvas{at}rdia.amz.nl.