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Prognosis
Children infected with meningitis before 1 year of age were at increased risk for disability at 5 years of age

https://doi.org/10.1136/ebm.7.2.60

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    (2001) BMJ 323, 533. Bedford H, de Louvois J, Halket S. , et al. . Meningitis in infancy in England and Wales: follow up at age 5 years.. Sep 8;. :. –6.
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 QUESTION: In children who survived meningitis during their first year of life, what are the sequelae at 5 years of age?

    Design

    Inception cohort of children who survived an acute attack of meningitis in their first year compared with children who did not have meningitis.

    Setting

    General practices in England and Wales, UK.

    Patients

    1717 children who contracted meningitis during their first year. Sex- and age-matched children from the same general practice as the index child formed the control group. Data at 5 years of age were available for 1584 children (92%) who had had meningitis and 1391 in the control group (94%).

    Assessment of prognostic factors

    General practitioners completed questionnaires on children that described any problems in neuromotor development, learning, vision, hearing, speech and language, and behaviour, and the presence of seizure disorders. Parents completed questionnaires on their child's health, development, and schooling. Gestational age, birthweight, the organism that caused the meningitis, and age at …

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    Footnotes

    • Sources of funding: Action Research and the Fayed Charitable Foundation.

    • For correspondence: Ms H Bedford, Institute of Child Health, London, UK. h.bedford{at}ich.ucl.ac.uk.

    • A modified version of this abstract also appears in Evidence-Based Nursing.