Article Text
PDF
Statistics from Altmetric.com
QUESTION: In children with persistent asthma, is montelukast a well tolerated and effective therapeutic option?
Design
Randomised {allocation concealed*}†, blinded (patients, clinicians, and {data collectors}†),* placebo controlled trial with 12 weeks of follow up.
Setting
93 centres in Africa, Australia, Europe, North America, and South America.
Patients
689 children who were 2 to 5 years of age (mean age 4 y, 59% boys, 56% white), had ≥ 3 episodes of asthma symptoms in the previous year, had a total asthma symptom score ≥ 1 (of 24) for ≥ 8 days during the 2 week placebo baseline period, and used β agonists for ≥ 8 days during the placebo baseline period. Exclusion criteria included asthma intubation and emergency department treatment or admission …
Request Permissions
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.