Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
QUESTION: In women with preterm, prelabour rupture of membranes, what are the effectiveness and safety of antibiotics for maternal and fetal outcomes?
Studies were identified by searching Medline (from 1966), the Cochrane Controlled Trials Register, key journals, and conference proceedings. Where possible, unpublished data were sought from investigators.
Studies were selected if they were randomised controlled trials, compared antibiotic use with placebo or different antibiotic regimens, included women with preterm (defined as < 37 wk) rupture of membranes, and reported clinically relevant outcomes.
Data were extracted on antibiotic type, outcomes, and study quality.
32 trials were identified, and 13 trials that randomised > 6000 women and their babies were included in the review. Most trials …
Source of funding: no external funding.
For correspondence: Ms S Kenyon, Leicester Royal Infirmary, Leicester, UK..