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A preoperative smoking intervention decreased postoperative complications in elective knee or hip replacement

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 QUESTION: In patients having elective knee or hip replacement, is a preoperative smoking intervention more effective than usual care for reducing postoperative morbidity and mortality?


Randomised {allocation concealed*}, blinded (outcome assessor),* controlled trial with follow up time to discharge.


3 university affiliated hospitals in Copenhagen, Denmark.


120 patients who were scheduled for primary elective hip or knee alloplasty and were daily smokers. Patients with a weekly alcohol intake > 35 units were excluded. 108 patients (90%) were included in the analysis (median age 65 y, 57% women).


At 6 to 8 weeks before surgery, 60 patients were allocated to the smoking intervention and were offered a weekly meeting with the project nurse. At the first meeting, a Fagerstöm …

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  • Sources of funding: Danish Research Councils; Danish Ministry of Health; Director Danielsen’s Foundation. Pharmacia Upjohn sponsored the nicotine substitution products.

  • For correspondence: Dr A M Møller, Bispebjerg University Hospital, Copenhagen, Denmark. docamm{at}

  • A modified version of this abstract also appears in Evidence-Based Nursing.

  • * See glossary.

  • Information provided by author.