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QUESTION: In patients presenting with acute bronchitis, does verbal advice plus an information leaflet describing the uncertain value of antibiotics reduce antibiotic use more than verbal advice alone?
Randomised (unclear allocation concealment*), blinded (clinicians and data collectors),* controlled trial with 4 weeks of follow up.
3 general practices in Nottingham, UK.
259 patients ≥ 16 years of age who had acute bronchitis (ie, illness for ≤ 21 d; main symptom of cough; ≥ 1 of sputum production, dyspnoea, wheeze, or chest discomfort or pain; and no alternative explanation) and were not receiving medical attention for an underlying disease, such as asthma, heart disease, or diabetes. 47 patients were judged to need antibiotics immediately. 212 …