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QUESTION: In men with recurrent calcium oxalate stones and hypercalciuria, is a diet containing a normal amount of calcium but reduced amounts of animal protein and salt more effective than a traditional low calcium diet?
Randomised (unclear allocation concealment*), blinded (outcome assessors),* controlled trial with 5 years of follow up.
An outpatient department in Parma, Italy.
120 men (mean age 45 y) who had idiopathic hypercalciuria (urinary calcium excretion > 300 mg/d) on an unrestricted diet, recurrent formation of calcium oxalate stones ( ≥ 2 colic episodes with expulsion of stones or radiographic evidence of retained stones), no known condition commonly associated with calcium nephrolithiasis, no previous visit to a stone disease centre, and no current treatment for prevention of recurrent stones. 103 men (86%) completed the study (13 withdrew, 2 were lost …