You are here

Article Text

Article menu
Download PDFPDF
Therapeutics
Review: antiemetic drugs reduce nausea in early pregnancy

https://doi.org/10.1136/ebm.7.5.155

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    (2002) Cochrane Database Syst Rev 1, CD000145; Jewell D, Young G.. Interventions for nausea and vomiting in early pregnancy.. ;(. ):. (latest version 15 Jan 2001)..

    
 
 QUESTION: How effective are different treatments for nausea and vomiting in early pregnancy?

    Data sources

    Studies were identified by using the search strategy of the Cochrane Pregnancy and Childbirth Review Group, which includes searches of Medline and the Cochrane Controlled Trials Register and handsearches of 38 journals.*

    Study selection

    Studies were selected if they were randomised controlled trials of any treatments to reduce nausea and vomiting in pregnancy (NVP) at up to 20 weeks of gestation.

    Data extraction

    2 reviewers independently assessed studies for quality of allocation concealment and extracted data on study methods, participant characteristics, interventions, and nausea and vomiting outcomes.

    Main results

    23 trials were included. Antiemetic medication reduced nausea more than did placebo (12 RCTs) but caused more drowsiness and sleepiness (4 RCTs) (table). 3 trials compared Bendectin with placebo …

    View Full Text

    Footnotes

    • Source of funding: no external funding.

    • For correspondence: Dr D Jewell, University of Bristol, Bristol, UK. david.jewell{at}bristol.ac.uk.

    • ↵* An update is forthcoming with additional evidence about acupuncture, acupressure, and ginger.