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  • Tonsillectomy and adenotonsillectomy showed modest benefits in children moderately affected with recurrent throat infection

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Therapeutics
Tonsillectomy and adenotonsillectomy showed modest benefits in children moderately affected with recurrent throat infection

https://doi.org/10.1136/ebm.8.1.25

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    (2002) Pediatrics 110, 7; Paradise JL, Bluestone CD, Colborn DK, et al.. Tonsillectomy and adenotonsillectomy for recurrent throat infection in moderately affected children.. ;. :. –15.
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 QUESTION: In children moderately affected with recurrent throat infection, what is the effectiveness of tonsillectomy or adenotonsillectomy?

    Design

    Randomised {allocation concealed*}†, unblinded,* controlled trial with 3 years of follow up.

    Setting

    Children’s hospital in Pittsburgh, Pennsylvania, USA.

    Patients

    328 children between 3 and 15 years of age (60% girls) who were moderately affected with recurrent episodes of throat infection (tonsillitis, pharyngitis, or tonsillopharyngitis: {depending on age, 4–6 episodes in previous 1 y; or 6–8 in previous 2 y}†). Children were excluded if they required immediate removal of large tonsils or adenoids because of obstructive symptoms. Follow up was 83% at year 1.

    Intervention

    Children were stratified into those without obstructing adenoids, or recurrent or persistent otitis media (n=177; 3 way trial) and those having ≥1 of the above conditions (n=151; 2 way trial). Children in the 3 way trial were …

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