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  • Review: a short course of antibiotic treatment is as effective as a standard course in children with urinary tract infection

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Therapeutics
Review: a short course of antibiotic treatment is as effective as a standard course in children with urinary tract infection

https://doi.org/10.1136/ebm.8.2.52

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    (2002) Arch Dis Child 87, 118. Michael M, Hodson EM, Craig JC, et al.. Short compared with standard duration of antibiotic treatment for urinary tract infection: a systematic review of randomised controlled trials.. ;. :. –23.
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 QUESTION: In children with urinary tract infection (UTI), what is the effectiveness of short course (2−4 d) compared with standard duration (7–14 d) of antibiotic treatment?

    Data sources

    Studies in all languages were identified by searching Medline (1966 to February 2001), EMBASE/Excerpta Medica (1988 to February 2001), the Cochrane Library (Issue 1, 2001), bibliographies of relevant studies and textbooks, and conference abstracts.

    Study selection

    Studies were selected if they were randomised controlled trials (RCTs) or quasi RCTs, involved children aged 3 months to 18 years with culture proven symptomatic UTI, and compared a short course (2–4 d) with a standard duration (7–14 d) of antibiotic treatment. Only studies that used the same antibiotic in both the short and standard duration arms were …

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    Footnotes

    • For correspondence: Dr E Hodson, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia. Elisah{at}chw.edu.au

    • Source of funding: no external funding.