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The following articles are abstracted in the May/June 2003 issue of ACP Journal Club. The declarative title of each abstract as published in ACP Journal Club precedes the article citation.
Therapeutics
Anterior–posterior electrode position led to more cardioversion success in atrial fibrillation
Intravenous water-soluble amiodarone improved 24-hour survival in incessant ventricular tachycardia
Review: Concomitant aspirin use does not reduce the effectiveness of ACE inhibitors
Losartan did not differ from captopril for reducing all-cause mortality after acute myocardial infarction
Antimicrobial treatment did not reduce complications of urinary tract infection in diabetes and asymptomatic bacteriuria
Omeprazole was effective in the short term for uninvestigated dyspepsia
Balsalazide achieved symptomatic remission sooner than mesalamine for ulcerative colitis
Self-administered behavioral training was equal to training plus biofeedback or verbal feedback in urge incontinence
Prognosis
The long-term prognosis, measured by health status, disease process, and damage, is variable in early rheumatoid arthritis
Economics
Activated protein C was cost-effective for prolonging survival in a subgroup of patients with severe sepsis
Aetiology
Review: Elevated homocysteine levels are modestly associated with increased ischemic heart disease and stroke risk
Review: MTHFR TT genotype increases risk for coronary heart disease
Clinical prediction guide
A gene expression profile independently predicted outcome of disease in young women with breast cancer