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Review: oral protein and energy supplements reduce all cause mortality in elderly people

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 QUESTION: In elderly people living in the community or in hospital, are oral protein and energy supplements effective for improving clinical outcomes and nutritional status?

Data sources

Studies were identified by searching the Cochrane Library (2001, issue 1), Medline (1966 to February 2001), EMBASE/Excerpta Medica (1980 to March 2001), HealthSTAR (1975 to March 2001), CINAHL (1982 to January 2001), BIOSIS (1985 to March 2001), CAB abstracts (1973 to March 2001), and 4 databases of registered trials; hand searching 8 nutrition journals; scanning bibliographies of relevant articles; and contacting researchers and manufacturers of nutritional supplements for unpublished and ongoing trials.

Study selection

Studies were selected if they were randomised controlled trials (RCTs) comparing a protein and energy supplement with no intervention, a placebo, or an alternative supplement; assessed ≥1 relevant clinical outcome; and studied hospitalised or community dwelling elderly people with a minimum average age of …

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