Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
QUESTION: In patients with infectious mononucleosis (IM), how frequent are chronic symptoms? Are any risk factors associated with chronic symptoms? Which interventions, if any, are preventive?
Studies were identified by searching Medline, EMBASE/Excerpta Medica, PsycINFO, and CINAHL (to October 2001) and the Science and Social Sciences citation indices (to November 2001). The references of retrieved studies were checked.
English language studies were selected if they were cohort or intervention studies that explored the course of illness for >6 weeks after onset in uncomplicated IM.
A standard form was used to extract data on study design and methods, setting, patient characteristics, study purpose, definition of IM, ill health and recovery, predictors of delayed recovery, and main study outcomes.
16 articles of 14 studies (2 randomised controlled trials [RCTs], 1 quasi-RCT, 7 prospective cohort studies, and 4 retrospective cohort studies) were included. Sample sizes ranged from 25–337 patients, and follow up ranged from 2 months to 2 years. 5 studies reported <80% follow up and are not included in …