Article Text

Download PDFPDF

A topical cream containing glucosamine and chondroitin sulphate reduced joint pain in osteoarthritis of the knee
Free

Statistics from Altmetric.com


 
 QUESTION: In patients with osteoarthritis of the knee, is a topical cream containing glucosamine sulphate, chondroitin sulphate, and camphor more effective than placebo for relieving joint pain?

Design

Randomised (allocation concealed*), blinded (patients, healthcare providers, and data collectors)*, controlled trial with 8 weeks of follow up.

Setting

An outpatient clinic at Monash Medical Center, Australia.

Patients

63 patients with objectively documented osteoarthritis of the knee who had had knee pain rated >4 cm on a 10 cm visual analogue scale in one or both knees for >4 weeks. Exclusion criteria included women of childbearing age who were not using contraception or were pregnant, and patients who had a regular requirement for analgesia for conditions unrelated to osteoarthritis or had used oral or topical glucosamine in the previous 6 weeks. Follow up was 94% (mean age 63 y, 54% women).

Intervention

Patients were allocated …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.