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Therapeutics
Review: drugs do not improve symptoms in urinary urge incontinence and may have side effects

https://doi.org/10.1136/ebm.8.6.182

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    (2002) Obstet Gynecol 100, 1003. Haeusler G, Leitich H, van Trotsenburg M, et al.. Drug therapy of urinary urge incontinence: a systematic review.. ;. :. –16.
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 QUESTION: Is drug therapy effective for urinary urge incontinence (UI)?

    Data sources

    Studies published up to October 2000 were identified by searching Medline (from 1966), EMBASE/Excerpta Medica (from 1989), and the Cochrane Controlled Trials Register.

    Study selection

    Original English language studies were selected if they were randomised placebo controlled trials of drug therapies other than hormone therapy in patients with UI confirmed by urodynamic assessment and outcomes included ≥1 of subjective improvement, results of a urodynamic evaluation, or adverse effects.

    Data extraction

    3 independent investigators extracted data on number of patients, inclusion and exclusion criteria, type of drug, and outcomes. Quality of individual trials was assessed on the basis of the randomisation process, patient exclusions …

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