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QUESTION: Are certain psychosocial risk factors (stressors) associated with the development and progression of coronary heart disease (CHD)?
Reviews were identified by searching Medline, EMBASE/Excerpta Medica, and PsycINFO using 47 search terms to describe study design, outcomes, and stressors. Reference lists of reviews and personal files of the investigators were also searched.
Reviews were selected if they were published in English in peer reviewed journals after 1979 and included prospective studies with ≥100 patients, and if CHD outcomes included myocardial infarction, myocardial revascularisation, and CHD death.
2 investigators independently assessed the quality of the selected reviews using a validated 7 point score. For reviews with a score ≥4, data were extracted on years covered, reviewers’ backgrounds, …
Sources of funding: National Heart Foundation of Australia and Beyondblue: the National Depression Initiative.
For correspondence: Dr S J Bunker, National Heart Foundation, Melbourne, Victoria, Australia.