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Q In premenopausal women with abnormal uterine bleeding (AUB), what is the diagnostic accuracy of transvaginal ultrasonography (TVUS), transvaginal sonohysterography (SH), and diagnostic hysteroscopy (DH) with biopsy?
Clinical impact ratings GP/FP/Primary care ★★★★★☆☆
METHODS
Data sources:
Medline and EMBASE/Excerpta Medica (1980 to July 2001) and reference lists.
Study selection and assessment:
English language comparative studies that compared a diagnostic (TVUS, SH, and DH with biopsy) and reference test (histopathology combined with hysteroscopy or hysterectomy) in premenopausal women with menstrual symptoms that may be caused by uterine pathology. Studies had to meet minimum quality criteria, report sufficient data to calculate sensitivity and specificity, and present separate results for postmenopausal women if they comprised >40% of the sample.
Outcomes:
detection of endometrial hyperplasia, endometrial …
Footnotes
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For correspondence: Dr C M Farquhar, University of Auckland, Auckland, New Zealand. c.farquharauckland.ac.nz
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Source of funding: no external funding.